Cytotoxic effects of furazolidone on HEp-2 cell line.
نویسندگان
چکیده
The effects o/ Fumzolidone (N-(5-nitro-2-furfurylidene)-3-arnino-2-oxazoIidone) on ce11 growth and colony-forming ability of o continuous ce11 line (HEp-2) hnve been studied. Almost complete death of ce11 culture was obserued a t the concentrution of 50 &/m[ Fumzolidone, while 0.5 pglml treated ce118 did not ahow ony effect on viability and ce11 growth. In the presence of 5 %/m1 Fumzolidone, cells exhibited a doseand time-rehted growth inhibition. Thb effect urna partially reduced by removing the drug from the cultures. The colony-Jormingability of treoted cella wos almost completely inhibited.
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ورودعنوان ژورنال:
- Annali dell'Istituto superiore di sanita
دوره 23 1 شماره
صفحات -
تاریخ انتشار 1987